Projects 2019

Research Projects ongoing in 2019 or approved for funding in 2020

TRYP-ELIM: A demonstration project combining innovative case detection, tsetse control and IT to eliminate sleeping sickness at district level in the Democratic Republic of Congo
Boelaert, M. – Epidemiology and Control of Neglected Tropical Diseases
Bill & Melinda Gates Foundation
21/10/15 → 30/03/19

LeishShield MATI: A multi-disciplinary international effort to identify clinical, molecular and social factors impacting cutaneous leishmaniasis
Dujardin, J. – Molecular Parasitology
European Commission
1/04/18 → 31/03/22

SMART2D: A people-centred approach through Self-Management and Reciprocal learning for the prevention and management of Type-2-Diabetes
Marchal, B.- Health Systems
Van Damme, W. – International Health Policy
European Commission
1/01/15 → 31/03/19

A proof-of-concept trial to evaluate artesunate-mefloquine as a novel alternative treatment for schistosomiasis in Africa
Bottieau, E. – Tropical Medicine
Flemish Government – Department of Economy, Science & Innovation (SOFI)
1/10/18 → 30/09/22

A systemic insecticide to control zoonotic cutaneous leishmaniasis in Errachidia province – Southeastern Morocco: an intervention trial for an innovative vector control tool
Boelaert, M., – Epidemiology and Control of Neglected Tropical Diseases
Flemish Government – Department of Economy, Science & Innovation (SOFI)
1/11/18 → 31/10/22

Accès à la prophylaxie pré-exposition au VIH hommes qui ont des relations sexuelles avec d’autres hommes : étude de l’acceptabilité et de la faisabilité dans les cliniques associatives d’Afrique de l’Ouest
Laga, M. – International HIV/AIDS policy
The Global Fund to Fight Aids
1/12/17 → 30/11/20

ALERRT: African CoaLition for Epidemic Research, Response and Training
van Griensven, J. – HIV and Neglected Tropical Diseases
European & Developing Countries Clinical Trials Partnership
01/12/2017 → 30/11/2022

Emmonsia: An investigation into the geographical distribution, host species, burden of disease and optimal diagnosis and treatment of Emmonsia hoerikwaggiana infections.
Büscher, P.- Diagnostic Parasitology
Kenyon, C. – STD
Fonds voor Wetenschappelijk Onderzoek
1/01/14 → 31/12/19

MAD-LEI: Aneuploidy and mosaicism: a strategy for early adaptation todrug pressure in Leishmania
Dujardin, J. – Molecular Parasitology
Flemish Government – Department of Economy, Science & Innovation (SOFI)
1/10/18 → 31/12/23

MASSIV: Anthropological research and community participation to facilitate mass drug administration of iverctmetin and dyhidroartemisin-piperaquine as an additional intervention for malaria elimination
Peeters, K. – Medical Anthropology
Medical Research Council
1/01/18 → 30/09/20

AZM4NTD: Azithromycin and opportunities for integrated control of Neglected Tropical Diseases
Inocêncio da Luz, R., PI, Epidemiology and Control of Neglected Tropical Diseases
Institutional Research Funds (Pump Priming Project)
1/11/18 → 31/10/19

Cryptic human and animal reservoirs compromise the sustained elimination of gambiense-human African trypanosomiasis in the Democratic Republic of the Congo
Büscher, P. – Diagnostic Parasitology
Flemish Government – Department of Economy, Science & Innovation (SOFI)
1/12/18 → 30/11/23

DIAMA: Culture free diagnosis and follow-up of multidrug resistant tuberculosis patients
de Jong, B. – Mycobacteriology
European & Developing Countries Clinical Trials Partnership
1/06/16 → 31/05/21

RBF-TBCare: Designing and evaluating provider results-based financing for tuberculosis care in Georgia: understanding costs, mechanisms of effect and impacts
Marchal, B. – Health Systems
MRC/ESRC/DFID/Wellcome Trust
1/03/17 → 1/03/21

iMash: Developing, Testing and Optimizing Patient Education and Counseling in HIV Prevention through Digital Self-Managementand Group Counseling among Men having Sex with Men
Laga, M. – International HIV/AIDS policy
Koning Boudewijnstichting
1/01/16 → 30/06/19

Development and proof-of-concept validation of a low-cost tropicalized device detecting bacterial growth in equipment-free blood cultures
Hardy, L. – Tropical Laboratory Medicine
Institutional Research Funds (Pump Priming Project)
1/09/18 → 31/08/19

iElisa HAT II: Development of a high-throughput inhibition ELISA to replace immune trypanolysis for post-elimination monitoring of gambiense-HAT
Büscher, P. – Diagnostic Parasitology
Bill & Melinda Gates Foundation
1/10/18 → 30/09/20

SeTPAT: Development of an antigen test for the diagnosis of syphilis
Kenyon, C. – STD
Koning Boudewijnstichting
1/01/18 → 30/11/19

ARTHROPOD: Development of specific and highly sensitive mulit-pathogen laboratory tests for the simultaneous and differential detection of arthropod-borne viruses
Ariën, K. – Virology
Agentschap voor Innovatie door Wetenschap en Technologie
1/08/17 → 31/07/20

iTECT-HAT: Diagnostic tools for human African trypanosomiasis elimination and clinical trials
Büscher, P. – Diagnostic Parasitology
European & Developing Countries Clinical Trials Partnership
1/02/16 → 31/01/21

TRYP-ELIM-BDD: Eliminating Human African Trypanosomiasis in the three (formerly) Bandundu provinces, the Democratic Republic of Congo.
Boelaert, M. – Epidemiology and Control of Neglected Infectious Diseases
Bill & Melinda Gates Foundation
1/11/16 → 31/12/21

Elucidating unique host-virus-parasite interaction with unseen depth an breadth
van Griensven, J., – HIV and Neglected Tropical Diseases
Institutional Research Funds (Pump Priming Project)
1/09/18 → 30/08/19

EmERGE: Evaluating mHealth technology in HIV to improve Empowerment and healthcare utilisation: Research and innovation to Generate Evidence for personalised care
Florence, E. – HIV/STD Clinic
European Commission
1/05/15 → 30/04/20

SOLID: Evaluation of an antibody detecting point-of-care test for the detection of Taenia Solium Taeniasis and (neuro) cysticercosis in communities and primary care settings of highly endemic, resource-poor areas in Tanzania and Zambia, including training of- and technology transfer to the regional Reference Laboratory and health centres
Dorny, P. – Veterinary Helminthology
European & Developing Countries Clinical Trials Partnership
1/09/16 → 31/08/20

Trebucq study: Evaluer l’efficacité et la tolérance d’un régime thérapeutique court sur 9 mois pour la tuberculose multirésistante
de Jong, B. – Mycobacteriology
The International Union Against Tuberculosis & Lung Disease
1/03/13 → 30/06/19

BURULI ULCUS: Global spread and transmission dynamics of Mycobacterium ulcerans
Eddyani, M. – Mycobacteriology
Flemish Government – Department of Economy, Science & Innovation (SOFI)
1/07/13 → 30/06/19

Greater Mekong Subregion Elimination of Malaria through Surveillance (GEMS) Program
Peeters, K. – Medical Anthropology
Bill & Melinda Gates Foundation
1/09/18 → 31/10/19

HEPATITIS C: Hepatitis C treatment for HIV patients in resource-poor countries: is a public health approach possible
Lynen, L. – HIV
van Griensven, J. – HIV and Neglected Tropical Diseases
Florence, E. – HIV/STD Clinic
Flemish Government – Department of Economy, Science & Innovation (SOFI)
1/07/14 → 30/06/19

DAA_HepC_HIV_MS: Hepatitis C virus direct acting antiviral (DAA) treatment success and its impact on transmission dynamics in HIV/HCV co-infected MSM
Buvé, A. – Epidemiology and Control of HIV/STD
Fonds voor Wetenschappelijk Onderzoek (Fundamenteel Onderzoeksproject)
1/01/17 → 31/12/20

Identification of epitopes in the alphaviral envelope that confer infectivity for human and mosquito cells.
Bartholomeeusen, K. – Virology
Fonds voor Wetenschappelijk Onderzoek (Krediet aan Navorsers)
1/01/18 → 31/12/20

IMMCYTE: Immuno Cytometry : Phenotyping immune cellular components, in the context of HBV, HIV and AD, by new, advanced technologies
Vanham, G. – Virology
Agentschap voor Innovatie door Wetenschap en Technologie
18/01/18 → 17/01/20

R2STOP Leprosy: Improved understanding of ongoing transmission of leprosy in the Comoros, a region hyperendemic for the disease
de Jong, B. – Mycobacteriology
Hasker, E. – Epidemiology and Control of Neglected Tropical Diseases
Research to Stop
1/01/17 → 31/12/19

HIV-NANOVA: Rationeel ontwerp van een therapeutisch vaccin tegen HIV-1 gebaseerd op een nieuwe formulering van nanopartikel
Vanham, G.- Virology
Fonds voor Wetenschappelijk Onderzoek
1/01/16 → 31/12/20

ILIAS: Invasive Lineages of AMR Salmonella, Trojan Horses in Africa
Van Puyvelde, S.- Diagnostic Bacteriology
Institutional Research Funds (Pump Priming Project)
1/10/18 → 30/09/19

EUKARYOTE: Kinetoplast genomics for the fine-scale study of hybrid zones in eukaryote parasites
Van den Broeck, F. – Molecular Parasitology
Fonds voor Wetenschappelijk Onderzoek (Krediet aan Navorsers)
1/01/17 → 31/12/19

La PrEP comme nouvel outil pour la prévention du VIH combinéune étude qualitative complémentaire d’un projet de démonstration de la PrEP en cours chez les HSH en Afriquede l’Ouest
Laga, M. – International HIV/AIDS Policy
A.N.R.S. Agence Nationale de Recherche Scientifique
1/08/18 → 31/07/21

MINIlab: Development of a small-scale, quality-assured, stand-alone, and transportable clinical bacteriology laboratory
Jacobs, J. – Tropical Laboratory Medicine
MSF France
1/03/18 → 31/12/19

MEMO: Monitoring van exotische steekmuggen in België
Van Bortel, W. – Medical Entomology
Vlaamse, Waalse en Brusselse overheden en de FOD Volksgezondheid, Veiligheid van de Voedselketen
1/07/17 → 30/06/20

PregnAnZi: Pre-delivery administration of azithromycin to prevent neonatal sepsis and death
Peeters, K. – Medical Anthropology
Medical Research Council
1/01/18 → 31/12/19

GENTOOL: Novel genetic tools to study the molecular basis of drug resistance in Trypanosoma congolense
Brasseur, A. – Veterinary Protozoology
Institutional Research Funds (Pump Priming Project)
1/10/18 → 30/09/19

Novel high-dose tuberclosis retreatment regimens: How to overcome resistance without creating more
Decroo, T. – HIV/AIDS
Fonds voor Wetenschappelijk Onderzoek (Postdoctoraal mandaat)
1/10/18 → 30/09/21

A multi-omic approach to characterize gene dosage compensation in Leishmania
Cuypers, B. – Molecular Parasitology
Fonds voor Wetenschappelijk Onderzoek (Postdoctoraal mandaat)
1/10/18 → 30/09/21

A study of the dynamics between sexual risk behavior, social context and the use of Pre-Exposure Prophylaxis among men who have sex with men: longitudinal and international mixed-method research
Reyniers, T. – International HIV/AIDS policy
Fonds voor Wetenschappelijk Onderzoek (Postdoctoraal mandaat)
1/10/18 → 30/09/21

Novel high-dose tuberculosis retreatment regimens: How to overcome resistance without creating more
Lynen, L. – HIV/AIDS
Flemish Government – Department of Economy, Science & Innovation (SOFI)
1/10/18 → 30/09/24

Operational research to sustain VL elimination and break transmission in India
Boelaert, M. – Epidemiology and Control of Neglected Tropical Diseases
Bill & Melinda Gates Foundation
1/07/18 → 31/12/19

Persistent T-cell dysfunction in synergistic VL-HIV co-infection
Adriaensen, W. – HIV and Neglected Tropical Diseases
Fonds voor Wetenschappelijk Onderzoek (Postdoctoraal Mandaat)
1/10/17 → 30/09/20

PEOPLE: Post exposure prophylaxis for leprosy in the Comoros and Madagascar
Hasker, E. – Epidemiology and Control of Neglected Tropical Diseases
European & Developing Countries Clinical Trials Partnership
1/09/18 → 31/08/22

PREDICT.VL: Predicting visceral leishmaniasis in HIV infected patients: how to screen and who to treat
van Griensven, J. – HIV and Neglected Infectious Diseases
Lynen, L. – HIV/AIDS
Flemish Government – Department of Economy, Science & Innovation
1/07/14 → 30/06/19

PReGo: Preventing Resistance in Gonorrhoea (PReGo) Study
Kenyon, C. – STD
Buyze, J. – Clinical Trials Unit
Crucitti, T. – Reference Laboratory HIV/STD
Vuylsteke, B. – International HIV/AIDS Policy
Soentjens, P. – Travel Clinic
Fonds voor Wetenschappelijk Onderzoek (Toegepast Biomedisch Onderzoek)
1/10/18 → 30/09/22

RIPSEC: Renforcement Institutionnel pour des Politiques de Santé basées sur l’Evidence en République Démocratique du Congo
Criel, B. – Health Financing
European Commission
24/12/14 → 23/12/19

ArboviroseTrans: Role of human movement in relation to popular spots in the spatiotemporal dimension of vectorial arbovirus transmission?
Vanlerberghe, V – General Epidemiology and Disease Control
Fonds voor Wetenschappelijk Onderzoek (Krediet aan Navorsers)
1/01/18 → 31/12/19

SETA: Severe Typhoid in Africa Program
Jacobs, J. – Tropical Laboratory Medicine
International Vaccine Institut
1/04/17 → 30/06/19

CYSTISTOP: Sofi Taenia solium elimination
Dorny, P. – Veterinary Helminthology
Berkvens, D. – Veterinary Biostatistics and Epidemiology
Flemish Government – Department of Economy, Science & Innovation
1/09/14 → 31/08/20

SPEED: Supporting Policy Engagements for Evidence Based Decisions for Universal Health Coverage in Uganda
Criel, B. – Health Financing
van de Pas, R. – International Health Policy
European Commission EuropeAid Co-operation Office
1/03/15 → 29/02/20

STREAM 2: The evaluation of a standardized treatment regimen of anti-tuberculosis drugs for patients with MDR-TB
de Jong, B.- Mycobacteriology
Vital Strategies
1/10/15 → 30/06/22

Equity-LA II: The impact of alternative care integration strategies on Health Care Networks’ performance in different Latin American health systems
Unger, J. – Public Sector Health Care
European Commission
1/08/13 → 31/07/19

VivaxAPMEN: The Vivax working group of the Asian Pacific Malaria Elimination Network
Peeters, K. – Medical Anthropology
Bill & Melinda Gates Foundation
13/11/16 → 31/12/19

HERMETIC: Using mathematical modelling to determine the number and characteristics of people living with undiagnosed HIV to inform targeted and innovative HIV testing
Laga, M. – International HIV/AIDS Policy
Agentschap voor Innovatie door Wetenschap en Technologie
1/11/15 → 30/04/19

TMRC-3: Visceral Leishmaniasis in Bihar State, India
Boelaert, M. – Epidemiology and Control of Neglected Tropical Diseases
National Institutes of Health – Tropical Medicine Research Centers
1/08/17 → 31/03/22

Whole Genome Sequencing to streamline TB diagnosis, improve TB surveillance and optimize individualized TB treatment a pragmatic trial
Rigouts, L. – Mycobacteriology
Fonds voor Wetenschappelijk Onderzoek – Toegepast Biomedisch Onderzoek met Wetenschappelijke finaliteit
1/10/18 → 30/09/22

WomenHIV_Africa: Young Women and HIV in Africa
Laga, M. – International HIV/AIDS Policy
Fondation de Luxembourg
1/01/17 → 1/02/22

ZikaPLAN: Zika Preparedness Latin American Network Adressing the urgent research gaps against the Zika virus and other emerging threats in Latin America
Ariën, K. – Virology
European Commission
1/10/16 → 30/09/20

Nodding: An Interdisciplinary Study Contributing to the Identification of the Cause of Nodding Syndrome In Four Countries
Peeters, K. – Medical Anthropology
Boelaert, M. – Epidemiology and Control of Neglected Tropical Diseases
Flemish Government – Department of Economy, Science & Innovation (SOFI)
1/08/14 → 31/12/18

ISALA: Analytical treatment interruption in HIV positive patients with low viral reservoir to evaluate the potential of a functional cure
Florence, E. – HIV/STD clinic
Agency for Innovation by Science & Technology
1/11/14 → 31/10/18

Carbapenem resistance in Enterobacteriaceae: diagnostic value of the small RNA landscapes
Deborggraeve, S. – Diagnostic Bacteriologyr
Jacobs, J. – Tropical Laboratory Medicine
Fonds voor Wetenschappelijk Onderzoek
1/01/15 → 31/12/18

MNSIRSES: Clinical and public health research to improve maternal and newborn health & to control sexually transmitted infections
De Brouwere, V. – Maternal and Reproductive Health
Kenyon, C. – STD
European Commission
1/01/14 → 30/06/18

MobEbola2.0: Conduite d’une mission de mobilisation 2.0 des équipes-cadres de district dans la lutte contre les maladiesà potentiel épidémique
Meessen, B. – Health Economicsr
Unicef Western & Central
20/09/15 → 30/04/18

EUROLEISHNET: Control of leishmaniasis, from bench to bedside and community
Boelaert, M. – Epidemiology and Control of Neglected Tropical Diseases
Büscher, P. – Diagnostic Parasitology
Dujardin, J. – Molecular Parasitology
European Commission
1/01/15 → 31/12/18

iELISA HAT: Development of a high-throughput inhibition ELISA to replace immune trypanolysis for post-elimination monitoring of gambiense-HAT
Büscher, P. – Diagnostic Parasitologyr
Bill & Melinda Gates Foundation
25/07/17 → 31/12/18

MalaSpot: Eco epidemiology of asymptomatic malaria hotspots, a prerequisite for malaria elimination?
Van Bortel, W. – Medical Entomology
Peeters, K. Medical Anthr- opology
Flemish Government – Department of Economy, Science & Innovation (SOFI)
1/11/14 → 31/12/18

PROPEL: Effect of maternal Pneumococcal vaccination on early life
Peeters, K. – Medical Anthropology
Medical Research Council
1/04/15 → 31/12/18

BOFFA GUINEA: Effectiveness of tiny target technology in controlling tsetse vectors for HAT – Boffa study in Guinea
Boelaert, M. – Epidemiology and Control of Neglected Tropical Diseases
Liverpool School of Tropical Medicine
1/05/17 → 31/12/18

Gezondheidsproject Diabetes in Kinshasa, DR Congo
Marchal, B. – Health Systems
CISO vzw
1/01/15 → 31/12/18

High treatment failure rates in Trypanosoma brucei gambiense sleeping sickness: the interface between drug resistant parasites and advanced disease stage.
Van Reet, N. – Diagnostic Parasitology
Fonds voor Wetenschappelijk Onderzoek (Krediet aan Navorsers)
1/01/16 → 31/12/18

PrEP: HIV Prevention with Pre-Exposure Prophylaxis
Laga, M. – International HIV/AIDS policy
Fransen, C. – Reference Laboratory HIV/STD
Kenyon, C. – STD
Agency for Innovation by Science & Technology
1/11/14 → 15/06/18

WISH: Improving HIV prevention and sexual and reproductive health care in high risk women in Rwanda using lessons learned from previous Rinda Ubuzima projects
Buvé, A. – Epidemiology and Control of HIV/STD
European & Developing Countries Clinical Trials Partnership
1/01/16 → 30/06/18

WHOPES: Large scale field trial (Phase III)
Coosemans, M. – Medical Entomology
World Health Organisation
1/02/15 → 30/06/18

ARMADA: Ontwikkeling van een pan-arbovirus diagnostische test voor klinisch management van niet-malaria ziekten met koorts
Ariën, K. – Virology
Cnops, L. – Central Laboratory for Clinical Biology
Agency for Innovation by Science & Technology
1/03/15 → 28/02/18

RHOST: Reactive Household-based Self-administered Treatment against residual malaria transmission in a cluster-randomised trial
Peeters, K. – Medical Anthropology
Medical Research Council
1/10/15 → 31/12/18

Syndemic Resistance to Antibiotics
Peeters, K. – Medical Anthropology
International Food policy
1/07/18 → 31/12/18

The RNA editing space of the neglected genome in the major livestock African trypanosome parasite, Trypanosoma congolense.
Van den Broeck, F. – Molecular Parasitology
Institutional Research Funds (Pump Priming Project)
1/11/17 → 31/12/18

DFID-TRAC2: Tracking Resistance to Artemisirins Collaboration 2
Peeters, K. – Medical Anthropology
London School of Hygiene & Tropical Medicine
1/11/15 → 31/03/18

Trend and significance of INH resistance in DF Bdesh
de Jong, B. – Mycobacteriology
Damien Foundation Belgium
1/01/18 → 31/12/18
FQresistTrendBd: Trend of fluoroquinolone resistance among the MDR in DF Bangladesh
de Jong, B. – Mycobacteriology
Damien Foundation Belgium
1/01/17 → 31/12/18

FQresNewTB: Trends in fluoroquinolone resistance in new TB patients in Bangladesh and the subsequent rate of acquired drug resistance
de Jong, B. – Mycobacteriology
Damien Foundation Belgium
1/01/17 → 31/12/18

TIMIKA-TDRRC: Tropical Disease Research Regional Collaboration (TDRRC) Initiative: to strenghten health systems to prevent and reduce drug-resistant malaria and tuberculosis
Peeters, K. – Medical Anthropology
The Commonwealth of Australia
1/04/17 → 30/06/18

Service

Evaluating Feasible tools for etiological diagnosis of Fever to orientate empirical treatment in the returning traveler
Bottieau, E. – Tropical Medicine
BioFire Diagnostics LLC
15/06/18 → 14/06/21

Technical Assistance to the 2nd Nationwide DRS in Bangladesh.
de Jong, B. – Mycobacteriology
World Health Organisation
20/02/18 → 30/06/20

WHO SRL TB: Technical assistance and support by the SRL ITM to the NRLs of Georgia and Bangladesh and Proficiency testing for drug- susceptibility testing
de Jong, B. – Mycobacteriology
World Health Organisation
15/05/19 → 31/03/20

BCCM: BCCM Enterprise Resource Planning / Laboratory Management System
Rigouts, L. & Janssens, N.
Belgian Science Policy Office
1/01/11 → 31/12/21

TB MYCO: Studies, referentietaken en andere prestaties inzake Tuberculose en Buruli ulcus ten behoeve van Damiaanactie.
de Jong, B., Rigouts, L., Van Deun, A. & Janssens, N.
Damien Foundation Belgium
1/11/06 → 31/10/20

BCCM/ITM Mycobacteriënverzameling: Consolidatie en beheer van het BCCM Consortium als Belgisch “Biological Research Center” (BRC)
de Jong, B. – Mycobacteriology
Federaal Wetenschapsbeleid
1/01/20 → 31/12/20